What is crossing over?

Crossing over is a process that produces new combinations (recombinations) of genes by interchanging and exhanging of corresponding segments between non-sister chromatids of homologous chromosomes.

It occurs during pachytene of prophase I of meiosis. The term crossing over was coined by Morgan.

The mechanism of crossing over consists four sequential steps such as synapsis, tetrad formation, crossing over and terminalization.

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